In 1952, when "Che" Guevara (Gael García Bernal) was a medical student, he toured South America with his friend Alberto Granado (Rodrigo de la Serna) on a beat-up motorcycle. Ernesto is a 23-year-old medical student specializing in leprosy. Alberto is a 29 years old biochemical. Both young people embark on a journey of discovery of the rich and complex human and social topography of the Latin American continent. The two left behind the familiar surroundings of Buenos Aires on a dilapidated 500cc Norton motorcycle, imbued with a romantic spirit of adventure. (FILMAFFINITY)